| 名稱 | AI-Edigene® KRAS p.G12D Reference Standard Pl |
| 型號(hào) | CBP10429 |
| 報(bào)價(jià) |  |
| 特點(diǎn) | AI-Edigene® KRAS p.G12D Reference Standard Plus |
產(chǎn)品搜索
相關(guān)文章
- 【產(chǎn)品推介】CD47&SIRPɑ 細(xì)胞篩選模型
- 黑色素瘤研究進(jìn)展一覽
- 【現(xiàn)貨上線】HRR-Related-28 Gene標(biāo)準(zhǔn)品
- 抗衰老全新靶點(diǎn)，抑制IL-11通路可延長(zhǎng)哺乳動(dòng)物壽命
- Cell Metab：雙信號(hào)通路失調(diào)協(xié)同促進(jìn)肺癌形成
- OX40&PD-1/L1雙免疫檢查點(diǎn)細(xì)胞篩選模型
- 細(xì)胞株鑒定指南
- 腫瘤細(xì)胞培養(yǎng)實(shí)驗(yàn)的主要用途
- 老靶點(diǎn)迭代突破創(chuàng)新：Her2靶點(diǎn)細(xì)胞模型
- 【產(chǎn)品推介】IL23抗體篩選模型
聯(lián)系我們
聯(lián)系人：蔣經(jīng)理
電話：4008750250
號(hào)碼：
手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號(hào)
Email： zhangxiangwen@cobioer.com
電話：4008750250
號(hào)碼：
手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號(hào)
Email： zhangxiangwen@cobioer.com
產(chǎn)品展示 / PRODUCTS
基因檢測(cè)標(biāo)準(zhǔn)品 > Mutation > CBP10429AI-Edigene® KRAS p.G12D Reference Standard Pl
- 詳細(xì)內(nèi)容
CBP10429 | |
| Format | Genomic DNA |
| Description | KRAS G12D is a hotspot mutation that lies within a GTP binding region of the Kras protein (UniProt.org). G12D results in decreased Kras GTPase activity and increased activation of downstream signaling, promotes tumor formation in mouse models (PMID: 16474405, PMID: 26037647, PMID: 22871572) and is transforming in cell culture (PMID: 29533785). |
| Technical Data | |
| DNA Change | c.35G>A |
| AA Change | p.G12D |
| Mutation type | Substitution - Missense |
| Zygosity | Homozygous |
| Allelic Frequency | 100% |
| Transcript | ENST00000311936 |
| Cosmic ID | COSM521 |
| Chr position(GRCh37) | chr12:25398284 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing |
|
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
" _ue_custom_node_="true">
會(huì)員_a.png)